Digestive Health
and disorders of gut-brain interaction
Disorders of Gut-Brain Interaction (DGBIs), previously known as Functional Gastrointestinal Disorders (FGIDs), refer to conditions in which the gastrointestinal (GI) system and the brain communicate in a way that affects digestive function. These disorders occur in the absence of identifiable structural or biochemical abnormalities but can involve a combination of:
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Motility disturbances
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Visceral hypersensitivity
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Altered mucosal and immune function
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Changes in gut microbiota
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Altered central nervous system processing
This definition reflects the evolving understanding of the multiple pathophysiological processes that lead to symptoms affecting quality of life. Common DGBIs include Irritable Bowel Syndrome (IBS), Functional Dyspepsia and Abdominal Migraine.
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Dr Kensey has a particular interest in novel integrative approaches to the management of DGBIs such as low dose naltrexone. Below are listed some articles on the current state of evidence for the use of low dose naltrexone for DGBIs and other indications:
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